Systems-Level Annotation of Metabolomics Data Reduces 25,000 Features to Fewer than 1,000 Unique Metabolites
نویسندگان
چکیده
منابع مشابه
Tags Re-ranking Using Multi-level Features in Automatic Image Annotation
Automatic image annotation is a process in which computer systems automatically assign the textual tags related with visual content to a query image. In most cases, inappropriate tags generated by the users as well as the images without any tags among the challenges available in this field have a negative effect on the query's result. In this paper, a new method is presented for automatic image...
متن کاملA workflow for UPLC-MS non-targeted metabolomic profiling in large human population-based studies
CC-BY-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. ABSTRACT Metabolomic profiling is an emerging technique in life sciences. Human studies using these techniques have been performed in a small number of individuals or have been targeted at a restricted number of metabolites. In this article,...
متن کاملمتابولومیکس، چشماندازی برای مردان نابارور: مقاله مروری
Infertility influences an estimated 20% of couples worldwide. The factors that can affect the fertility potential are equally distributed between men and women. Despite extensive research in male infertility, the etiology in majority of infertile men is unknown. In 2010, there was an opinion published in Nature asking a selection of leading researchers and policy-makers about what their future ...
متن کاملMeltDB: a software platform for the analysis and integration of metabolomics experiment data
MOTIVATION The recent advances in metabolomics have created the potential to measure the levels of hundreds of metabolites which are the end products of cellular regulatory processes. The automation of the sample acquisition and subsequent analysis in high-throughput instruments that are capable of measuring metabolites is posing a challenge on the necessary systematic storage and computational...
متن کاملUC2 search: using unique connectivity of uncharged compounds for metabolite annotation by database searching in mass spectrometry-based metabolomics
Summary For metabolite annotation in metabolomics, variations in the registered states of compounds (charged molecules and multiple components, such as salts) and their redundancy among compound databases could be the cause of misannotations and hamper immediate recognition of the uniqueness of metabolites while searching by mass values measured using mass spectrometry. We developed a search sy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017